Relationship of dental practitioners to rural primary care networks

Abstract still to be addedResidents of rural and remote communities have poorer oral health and less access to oral health services than people living in major cities. The populations of many rural and remote centres are not large enough to support a resident dentist and, in the absence of community oral health services, rural residents may present to non-dental primary care providers with oral health problems. The aim of this study was to describe strategies that can be used by primary care practitioners to improve the provision of oral health services to rural and remote communities. The specific objectives were to (i) map oral health services practices in rural communities across primary care providers (ii) assess the extent to which oral health problems impact on service provision by primary health care providers; (iii) assess the extent to which primary care networks could be more effectively utilised to improve the provision of oral health services to rural communities and to identify what interventions/strategies were most likely to be effective.The research reported in this paper is a project of the Australian Primary Health Care Research Institute which is supported by a grant from the Australian Government Department of Health and Ageing under the Primary Health Care Research Evaluation and Development Strategy

The paradox of going hungry when there is so much food : the perspective of vulnerable youth and their caseworkers

This study aimed to examine the food security challenges experienced among vulnerable youth in North West Tasmania. An exploratory, descriptive design was used to collect data through face-to-face interviews and focus group discussions with 22 young residents and with five stakeholders and representatives from different community and state organisations. The most significant finding of the study was that a proportion of young residents in the North West Coast of Tasmania were threatened by food insecurity, which was caused by a combination of factors including patterns of food consumption and dietary behaviours. Those with higher financial difficulty due to the lack of a stable job were significantly more vulnerable to food insecurity and faced a higher chance of having health problems. The findings of the project have many implications to improve the food security and lives of vulnerable youth

HIV Suppression among Patients on Treatment in Vietnam: A Review of HIV Viral Load Testing in a Public Urban Clinic in Ho Chi Minh City

Background. There are few reports of HIV viral load (VL) testing among patients on ART in Vietnam. Methods. From a public clinic in Ho Chi Minh City (HCMC), we reviewed cases of VL measurements from adults on ART. Results. We identified 228 cases. Median age was 30 years (27–34), 85% were male, and 77% had a history of IDU. The mean ART duration was 26 months (95% CI 25–27); d4T/3TC/NVP was the most common regimen. Viral suppression was seen in 160/228 (70%). Viremia (>1000 copies/mL) was associated with prior ART exposure (OR 5.68, P < .0001) and immunologic failure (OR 4.69, P = .0001). Targeted testing accounted for 13% of cases, only half of which yielded viremia. Conclusion. We demonstrate a high HIV suppression rate among patients on ART in HCMC, Vietnam. In this setting, routine testing detects viremia missed by targeted testing

Coordinated Container Migration and Base Station Handover in Mobile Edge Computing

Offloading computationally intensive tasks from mobile users (MUs) to a virtualized environment such as containers on a nearby edge server, can significantly reduce processing time and hence end-to-end (E2E) delay. However, when users are mobile, such containers need to be migrated to other edge servers located closer to the MUs to keep the E2E delay low. Meanwhile, the mobility of MUs necessitates handover among base stations in order to keep the wireless connections between MUs and base stations uninterrupted. In this paper, we address the joint problem of container migration and base-station handover by proposing a coordinated migration-handover mechanism, with the objective of achieving low E2E delay and minimizing service interruption. The mechanism determines the optimal destinations and time for migration and handover in a coordinated manner, along with a delta checkpoint technique that we propose. We implement a testbed edge computing system with our proposed coordinated migration-handover mechanism, and evaluate the performance using real-world applications implemented with Docker container (an industry-standard). The results demonstrate that our mechanism achieves 30%-40% lower service downtime and 13%-22% lower E2E delay as compared to other mechanisms. Our work is instrumental in offering smooth user experience in mobile edge computing.Comment: 6 pages. Accepted for presentation at the IEEE Global Communications Conference (Globecom), Taipei, Taiwan, Dec. 202

Vekstbedrifters sosiale nettverk

Denne bacheloroppgaven har som formål å undersøke hvilken effekt sosialt nettverk har for veksten til norske bedrifter. Dette vil bli gjort ved å undersøke graden av sosialt nettverk hos gasellebedrifter og sammenlikne dette opp mot en kontrollgruppe. Gasellebedrifter har en stor betydning for sysselsetting og verdiskapning i et land, på grunn av rask vekst, ekspansjon og omsetning (Rasmussen 2014). Arbeidsledighet er et stort problem, og Ringstad (2011) hevder at det er at av de mest sentrale økonomiske og politiske problemene som finnes. Ved å avdekke kriterier som kan hjelpe bedrifter til å vokse raskere, vil man kunne bidra til å øke antall arbeidsplasser som skapes. I Norge blir dette mer relevant, etter at oljebransjen har begynt å stagnere og det norske arbeidsmarkedet møter mer usikre tider. Resultatene av undersøkelsen vil være til stor hjelp for å øke forståelsen, og dermed bedre tilretteleggelse for vekst, som igjen vil føre til at det skapes mer verdi og arbeidsplasser i samfunnet. Vi benyttet oss av kvantitative undersøkelser, i form av spørreundersøkelser, for å kunne svare på problemstillingen: “I hvor stor grad påvirker sosialt nettverk veksten til gasellebedrifter?”. Utvalget som skal undersøkes, består av en gruppe gasellebedrifter og en tilsvarende kontrollgruppe bestående av små- og mellomstore bedrifter (SMB). Oppgaven vil argumentere for at sosialt nettverk kan bli sett på som et langsiktig konkurransefortrinn for bedrifter, ut fra et ressursbasert syn. Sosialt nettverk som fagfelt er omfattende, og vil bli delt inn i fire underkategorier; nettverkstetthet, nettverksposisjon, nettverksstyrke og nettverksstørrelse. Dette legger grunnlaget for våre fire hypoteser, som viste seg å ikke være signifikante. Undersøkelsen viste ikke noe signifikant forskjell på sosialt nettverk mellom gasellebedriftene og kontrollgruppen. Derimot viser undersøkelsen at alder og utdannelsenivået var lavere hos gasellebedrifter (daglig leder), enn hos kontrollgruppen. Dette kan sees i sammenheng med at gasellebedrifter ofte er yngre og mindre. Hvilken bransje bedriften opererer i og konjunkturen til økonomien vil kunne påvirke om en bedrift blir kategorisert som en gaselle. Hurtig vekst kan føre med seg mange nye utfordringer, som kan hindre optimal bruk av ressurser, som for eksempel vedlikehold og utnyttelsen av sosial kapital. Dette kan være problematisk for gasellebedrifter som opplever større vekst enn andre

A bioinformatics workflow for detecting signatures of selection in genomic data

The detection of “signatures of selection” is now possible on a genome-wide scale in many plant and animal species, and can be performed in a population-specific manner due to the wealth of per-population genome-wide genotype data that is available. With genomic regions that exhibit evidence of having been under selection shown to also be enriched for genes associated with biologically important traits, detection of evidence of selective pressure is emerging as an additional approach for identifying novel gene-trait associations. While high-density genotype data is now relatively easy to obtain, for many researchers it is not immediately obvious how to go about identifying signatures of selection in these data sets. Here we describe a basic workflow, constructed from open source tools, for detecting and examining evidence of selection in genomic data. Code to install and implement the pipeline components, and instructions to run a basic analysis using the workflow described here, can be downloaded from our public GitHub repository: http://www.github.com/smilefreak/selectionTools

Beyond First/Last Mile Active Transportation - BikeShare@UH

Bike sharing is a new green transportation solution that has been developed and adopted at various cities around the world. In this paper, we present the process and results of the design and prototypes that a group of undergraduate students developed for a BikeShare@UH program during Summer 2017. After presenting the detailed results of four project teams focusing on customer discovery, bike share station (BSS) location identification, cloud-based mobile computing platform for user engagement and bike share program operation and management, smart lock, and alternative energy source based on PV panel. With the phase one implementation at the University planned in Spring 2018, we anticipate gathering real time data and feedback to improve the system.Cockrell School of Engineerin

The use of fluorescence correlation spectroscopy to monitor cell surface β2‐adrenoceptors at low expression levels in human embryonic stem cell‐derived cardiomyocytes and fibroblasts

The importance of cell phenotype in determining the molecular mechanisms underlying β2- adrenoceptor (β2AR) function has been noted previously when comparing responses in primary cells and recombinant model cell lines. Here, we have generated haplotype-specific SNAP-tagged β2AR human embryonic stem (ES) cell lines and applied fluorescence correlation spectroscopy (FCS) to study cell surface receptors in progenitor cells and in differentiated fibroblasts and cardiomyocytes. FCS was able to quantify SNAP-tagged b2AR number and diffusion in both ES-derived cardiomyocytes and CRISPR/Cas9 genome-edited HEK293T cells, where the expression level was too low to detect using standard confocal microscopy. These studies demonstrate the power of FCS in investigating cell surface b2ARs at the very low expression levels often seen in endogenously expressing cells. Furthermore, the use of embryonic stem cell technology in combination with FCS allowed us to demonstrate that cell surface b2ARs internalise in response to formoterol-stimulation in ES progenitor cells but not following their differentiation into ES-derived fibroblasts. This indicates that the process of agonist-induced receptor internalisation is strongly influenced by cell phenotype and this may have important implications for drug treatment with long-acting b2AR agonists

Report of the Topical Group on Top quark physics and heavy flavor production for Snowmass 2021

This report summarizes the work of the Energy Frontier Topical Group on EW Physics: Heavy flavor and top quark physics (EF03) of the 2021 Community Summer Study (Snowmass). It aims to highlight the physics potential of top-quark studies and heavy-flavor production processes (bottom and charm) at the HL-LHC and possible future hadron and lepton colliders and running scenarios

CMB-S4: Forecasting Constraints on Primordial Gravitational Waves

CMB-S4---the next-generation ground-based cosmic microwave background (CMB) experiment---is set to significantly advance the sensitivity of CMB measurements and enhance our understanding of the origin and evolution of the Universe, from the highest energies at the dawn of time through the growth of structure to the present day. Among the science cases pursued with CMB-S4, the quest for detecting primordial gravitational waves is a central driver of the experimental design. This work details the development of a forecasting framework that includes a power-spectrum-based semi-analytic projection tool, targeted explicitly towards optimizing constraints on the tensor-to-scalar ratio, $r$, in the presence of Galactic foregrounds and gravitational lensing of the CMB. This framework is unique in its direct use of information from the achieved performance of current Stage 2--3 CMB experiments to robustly forecast the science reach of upcoming CMB-polarization endeavors. The methodology allows for rapid iteration over experimental configurations and offers a flexible way to optimize the design of future experiments given a desired scientific goal. To form a closed-loop process, we couple this semi-analytic tool with map-based validation studies, which allow for the injection of additional complexity and verification of our forecasts with several independent analysis methods. We document multiple rounds of forecasts for CMB-S4 using this process and the resulting establishment of the current reference design of the primordial gravitational-wave component of the Stage-4 experiment, optimized to achieve our science goals of detecting primordial gravitational waves for $r > 0.003$ at greater than $5\sigma$, or, in the absence of a detection, of reaching an upper limit of $r < 0.001$ at $95\%$ CL.Comment: 24 pages, 8 figures, 9 tables, submitted to ApJ. arXiv admin note: text overlap with arXiv:1907.0447